Study of miRNA Let-7 Involvement in Breast Cancer through the Light of Graph Theory and Canalizing Function

نویسندگان

  • Antara Sengupta
  • Camellia Ray
  • Pabitra Pal Choudhury
  • A. Ahmad
  • A. S. Ali
  • S. Ali
  • Z. Wang
  • D. Kong
  • F. H. Sarkar
  • Franziska Hinkelmann
  • Abdul Salam
چکیده

miRNAs are small, non-coding RNAs and of 21-25 nucleotide in size. They negatively regulate protein-coding mRNAs at the post-transcriptional level. miRNAs play very important roles in various biological processes like cell growth, differentiation, and development. Abnormal expressions of miRNAs can lead various diseases including cancer and therefore miRNAs are considered as strong diagnostic and therapeutic candidates for the treatment of human

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تاریخ انتشار 2014